ENHANCING ANIMAL WELL-BEING, IMMUNOCOMPETENCE, AND PERFORMANCE IN SWINE AND BEEF CATTLE
Location: Livestock Issues Research
Title: Live yeast and citrus pulp supplementation reduces the presence of rectal Salmonella without impairing performance in young pigs
Submitted to: American Society of Animal Science Southern Section Meeting
Publication Type: Abstract Only
Publication Acceptance Date: November 5, 2011
Publication Date: June 25, 2012
Citation: Sanchez, N.C., Carroll, J.A., Callaway, T.R., Chevaux, E., Rosener, D. 2012. Live yeast and citrus pulp supplementation reduces the presence of rectal Salmonella without impairing performance in young pigs [abstract]. Journal of Animal Science. 90:23(E-Suppl. 1).
The effect of supplementing the diets of young pigs with live yeast (LY) and/or citrus pulp (CP) on growth performance and the presence of Salmonella in various tissues following a dual lipopolysaccharide (LPS) and Salmonella challenge was evaluated. Forty barrows (26+/-0.2 day of age; 7.8+0.2 kg body weight), housed in individual stanchions (1.2 x 0.6 m) with ad libitum access to feed and water, were assigned to 1 of 4 treatments (n=10/treatment): 1) Control (C), fed a commercial starter diet; 2) LY, fed the commercial diet supplemented with LY (200 g/ton; Lallemand Specialties Inc.); 3) CP, fed the commercial diet supplemented with CP (5% as fed); and 4) LY and CP (LYCP), diet supplemented with LY (200 g/ton) and CP (5% as fed). On day 13, intraperitoneal temperature (TIP) loggers were inserted into all pigs. On day 20, pigs were administered LPS (25 microgram/kilogram body weight) intraveneously at 0 h, and then orally dosed with Salmonella typhimurium (10^6 colony forming units/pig) at 3 h. On dy 24, pigs were humanely euthanized for the collection of intestinal contents and lymph tissue. Pigs and feeders were weighed on day 0, 6, 13, 19, and 24. Pre-challenge average daily gain was greater (P<0.01) in C and CP compared to LY and LYCP pigs. Pre-challenge feed intake was greater (P=0.01) in C, LY and LYCP, while feed:gain was lower (P=0.04) in CP pigs. However, post-challenge feed intake was greater (P<0.01) in the C and LY pigs. Pre-challenge, LY, CP and LYCP had lower TIP than C (P<0.01). An LPS-induced increase in TIP occurred within 1 h (P<0.01) post-LPS. Salmonella also induced an increase in TIP at approximately 60 h. Post-challenge TIP was lowest in LY and CP (P<0.01), with no difference between C and LYCP (P=0.44). There was no treatment effect on Salmonella counts in ileum (P=0.11) and cecum (P=0.23) contents collected 99 h post-challenge. However, Salmonella counts were lower in the rectum of LY and CP pigs (P<0.01) and were lower in the lymph of LY pigs (P<0.01) compared to C pigs. These data suggest that feeding LY or CP can reduce rectal Salmonella content and the febrile response of young pigs to a dual LPS and Salmonella challenge without negatively affecting pig performance.