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ARS Home » Plains Area » Houston, Texas » Children's Nutrition Research Center » Research » Publications at this Location » Publication #267873
Title: Weight loss in individuals with metabolic syndrome given DASH diet counseling when provided a low sodium vegetable juice: A randomized controlled trial

Author
item SHENOY, S - University Of California
item POSTON, WS - University Of Missouri
item REEVES, R - Children'S Nutrition Research Center (CNRC)
item KAZAKS, A - Bastyr University
item HOLT, R - University Of California
item KEEN, C - University Of California
item CHEN, H - University Of California
item HADDOCK, C - University Of Missouri
item WINTERS, B - Campbell Soup Research
item KHOO, CS - Campbell Soup Research
item Foreyt, John - Children'S Nutrition Research Center (CNRC)

Submitted to: Nutrition Journal
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 2/23/2010
Publication Date: 2/23/2010
Citation: Shenoy, S.F., Poston, W.C., Reeves, R.S., Kazaks, A.G., Holt, R.R., Keen, C.L., Chen, H.J., Haddock, C.K., Winters, B.L., Khoo, C.H., Foreyt, J. 2010. Weight loss in individuals with metabolic syndrome given DASH diet counseling when provided a low sodium vegetable juice: A randomized controlled trial. Nutrition Journal. 9(8): 1-12.

Interpretive Summary: Metabolic Syndrome, a collection of metabolic risk factors for type 2 diabetes and cardiovascular disease, is one of the fastest growing disease entities in the world. Weight reduction is a key component to improving all aspects of metabolic syndrome. Diets rich in vegetables and fruits have a number of benefits in helping individuals reach and achieve healthy weights. This study examined whether including an easily accessible, portable vegetable-based beverage as part of the calorie-controlled Dietary Approaches to Stop Hypertension (DASH) diet would increase vegetable intake and improve clinical characteristics of the metabolic syndrome. Results demonstrated that participants who consumed vegetable juice lost more weight, on average, than the participants who did not drink vegetable juice. Further, increasing vegetable juice consumption was effective at improving Vitamin C and potassium intake. The findings suggest that incorporating vegetable juice is a simple and effective way to help increase daily vegetable intake while also aiding in weight loss when paired with a calorie restricted diet.

Technical Abstract: Metabolic syndrome, a constellation of metabolic risk factors for type 2 diabetes and cardiovascular disease, is one of the fastest growing disease entities in the world. Weight loss is thought to be a key to improving all aspects of metabolic syndrome. Research studies have suggested benefits from diets rich in vegetables and fruits in helping individuals reach and achieve healthy weights. The objective of this study was to evaluate the effects of a ready to serve vegetable juice as part of a calorie-appropriate Dietary Approaches to Stop Hypertension (DASH) diet in an ethnically diverse population of people with Metabolic Syndrome on weight loss and their ability to meet vegetable intake recommendations, and on their clinical characteristics of metabolic syndrome (waist circumference, triglycerides, HDL, fasting blood glucose and blood pressure). A secondary goal was to examine the impact of the vegetable juice on associated parameters, including leptin, vascular adhesion markers, and markers of the oxidative defense system and of oxidative stress. A prospective 12 week, 3 group (0, 8, or 16 fluid ounces of low sodium vegetable juice) parallel arm randomized controlled trial. Participants were requested to limit their calorie intake to 1600 kcals for women and 1800 kcals for men and were educated on the DASH diet. A total of 81 (22 men & 59 women) participants with Metabolic Syndrome were enrolled into the study. Dietary nutrient and vegetable intake, weight, height, leptin, metabolic syndrome clinical characteristics and related markers of endothelial and cardiovascular health were measured at baseline, 6-, and 12-weeks. There were significant group by time interactions when aggregating both groups consuming vegetable juice (8 or 16 fluid ounces daily). Those consuming juice lost more weight, consumed more Vitamin C, potassium, and dietary vegetables than individuals who were in the group that only received diet counseling (p < 0.05). The incorporation of vegetable juice into the daily diet can be a simple and effective way to increase the number of daily vegetable servings. Data from this study also suggest the potential of using a low sodium vegetable juice in conjunction with a calorie restricted diet to aid in weight loss in overweight individuals with metabolic syndrome.