Technical Abstract: Hydroxypropyl methylcellulose (HPMC) is a substituted cellulose that reduces serum cholesterol at modest intake levels. HPMC has also been used for decades in gluten-free breads at a level to optimize loaf volume. Because consumers resist the consumption of whole wheat breads, we evaluated the sensory and physical properties of all oat and barley breads incorporating HPMC. Oat and barley also contain ß-glucan, a glucose polymer similar to HPMC that also lowers cholesterol. The textural and sensory properties of the breads were determined by instrumental and chemical methods, and sensory panels. HPMC increased the loaf volume of the breads by up to two times and decreased hardness immediately after baking and after up to 3 days of storage. Barley bread with HPMC was rated the highest in overall acceptability by sensory panelists compared to oat and wheat breads with or without HPMC.