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United States Department of Agriculture

Agricultural Research Service

Research Project: GENETIC AND IMMUNE STRATEGIES TO CONTROL MUCOSAL PATHOGENS OF SWINE Title: Progress in Porcine Respiratory and Reproductive Syndrome Virus Biology and Control

Authors
item Lunney, Joan
item Rowland, Raymond -

Submitted to: Virus Research
Publication Type: Review Article
Publication Acceptance Date: March 15, 2010
Publication Date: December 1, 2010
Repository URL: http://www.sciencedirect.com/science?_ob=PublicationURL&_tockey=%23TOC%234934%232010%23998459998%232662741%23FLA%23&_cdi=4934&_pubType=J&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=6956098&md5=ae2e4fa94ef5a610965f00f0872f7cff
Citation: Lunney, J.K., Rowland, R.R. 2010. Progress in Porcine Respiratory and Reproductive Syndrome Virus Biology and Control. Virus Research Special Issue. 154(1-2):1-192.

Interpretive Summary: Drs. Lunney and Rowland served as Co-Editors for this Virus Research special issue on “Progress in porcine respiratory and reproductive syndrome virus biology.” This issue starts with an overview manuscript that summarizes the history of Porcine Reproductive and Respiratory Syndrome (PRRS), the syndrome that caused reproductive and respiratory problems in swine in the late 1980’s and that is associated with the high morbidity and mortality for “Porcine high fever disease,” reported in China starting in 2006 and spreading to Vietnam and Cambodia in 2010. The research reviews and articles presented in this special issue of Virus Research highlight the virus, its pathogenesis, epidemiology, immunology, vaccinology and host genetic control. It is hoped that these articles will stimulate new ideas and collaborations between researchers and swine veterinarians to improve our understanding of PRRS and PRRSV and help eliminate this economically important disease of swine.

Technical Abstract: This special issue of Virus Research is focused on Porcine Reproductive and Respiratory Syndrome (PRRS). It contains 19 reviews invited by CoEditors, Joan K. Lunney and R.R.R. Rowland, on this arterivirus, referred to as PRRS virus (PRRSV), and associated issues. It targets areas such as: phylogenetic and evolutionary analysis of PRRSV, development of infectious clones and their use in identifying viral control mechanisms, viral receptors, host immunity and new vaccine design, and viral ecology, epidemiology, and elimination protocols. The reviews address presents areas of research and gaps that inhibit PRRS elimination progress. It highlights efforts targeted at production of effective vaccines and current plans for PRRS control programs. These reviews should stimulate discussion and collaboration between researchers and swine veterinarians throughout the world to provide answers that enhance our understanding of PRRS and PRRSV in an effort to eliminate this economically important disease.

Last Modified: 9/23/2014