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United States Department of Agriculture

Agricultural Research Service

Research Project: DISCOVERY AND DEVELOPMENT OF NATURAL PRODUCT-BASED WEED MANAGEMENT METHODS

Location: Natural Products Utilization Research

Title: Natural toxins for use in pest management

Authors
item Duke, Stephen
item Cantrell, Charles
item Meepagala, Kumudini
item Wedge, David
item Tabanca, Nurhayat
item Schrader, Kevin

Submitted to: Toxins
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: July 26, 2010
Publication Date: July 29, 2010
Citation: Duke, S.O., Cantrell, C.L., Meepagala, K.M., Wedge, D.E., Tabanca, N., Schrader, K. 2010. Natural toxins for use in pest management. Toxins. 2:1943-1962.

Interpretive Summary: Natural toxins are a source of new chemical classes of pesticides, as well as environmentally and toxicologically safer molecules than many of the currently used pesticides. Furthermore, they often have molecular target sites that are not exploited by currently marketed pesticides. There are highly successful products based on natural compounds in the major pesticide classes. These include the herbicide glufosinate (synthetic phosphinothricin), the spinosad insecticides, and the strobilurin fungicides. These and other examples of currently marketed natural product-based pesticides, as well as natural toxins that show promise as pesticides from our own research are discussed.

Technical Abstract: Natural toxins are a source of new chemical classes of pesticides, as well as environmentally and toxicologically safer molecules than many of the currently used pesticides. Furthermore, they often have molecular target sites that are not exploited by currently marketed pesticides. There are highly successful products based on natural compounds in the major pesticide classes. These include the herbicide glufosinate (synthetic phosphinothricin), the spinosad insecticides, and the strobilurin fungicides. These and other examples of currently marketed natural product-based pesticides, as well as natural toxins that show promise as pesticides from our own research are discussed.

Last Modified: 9/22/2014