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United States Department of Agriculture

Agricultural Research Service

Research Project: EPIDEMIOLOGY, ECOLOGY, AND MOLECULAR GENETICS OF ANTIMICROBIAL RESISTANCE IN PATHOGENIC AND COMMENSAL BACTERIA FROM FOOD ANIMALS Title: Salmonella Smorgasbord: The Problem with too Many Choices

Author
item Cray, Paula

Submitted to: International Association for Food Protection
Publication Type: Abstract Only
Publication Acceptance Date: July 6, 2010
Publication Date: August 2, 2010
Citation: Cray, P.J. 2010. Salmonella Smorgasbord: The Problem with too Many Choices. International Association for Food Protection. S17. 9.

Technical Abstract: Although hundreds of articles are written about Salmonella each year, it continues to command top billing as a food borne pathogen. We have revisited the same issues over a period of time without hitting upon a ‘eureka’ moment. Often, we tend to travel in the comfort zone, bringing in the latest and greatest technology which, while providing insight regarding specific gene functions, has not provided us with the magic control solution. This symposium is meant to take us out of the comfort zone, sometimes back to areas we long thought of as complete, of little significance or too hard to deal with. For “Niche Displacement: Can you really find a new renter?” the talk will focus on issues surrounding control. There is a preponderance of evidence that if you control for one serotype another comes in. The notion that you can ‘get rid’ of a specific serotype may not solve the problem as the niche seems to require filling by Salmonella, regardless of serotype. This is meant to be a thought provoking talk without the intent to talk about competitive exclusion, prebiotics or probiotics. A compelling example of what has happened over the last 11 years with Kentucky, Enteritidis, Heidelberg, Typhimurium and Typhimurium 5- should make the audience take pause. . Additionally, what may not be present in plant may appear at retail! In “Country Specific Serotypes: Why Some Salmonella Never Seem to Travel” the talk will compare and contrast serotypes between countries. The goal would be to postulate why some seem rooted in one country. The DT104 story in England or Sophia in Australia are good examples of a widespread problem that hasn’t really travelled well. “The Slugfest – Why Some Salmonella Outcompete Others” explores the differences between salmonella serotypes in recovery and competition during cultivation both in vivo and in vitro. Although some may ask why this has to be revisited, there are serious implications as regulations are being made on the data which can be impacted by cultivation methods. “An Ibuprofen Moment: A Regulatory Challenge” will focus on the challenges associated with developing regulations around Salmonella. This could also be given by someone who can speak to trade issues. A blast from the past? Why we need to build better a better host” will focus on the host/bug interactions, immunity and what molecular biology at the gut level can do for us today. If we can’t control salmonella by conventional means, will control in the host really work? Finally, “Give it Your best Shot: The Chemical Control Conundrum” will focus around the myriad of serotypes found in a plant and how one chemical intervention may not necessary provide universal control. Therefore, if you can control it on farm but not in the plant, how much do you really gain?

Last Modified: 11/22/2014
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