Location: Plant Gene Expression Center Albany_CA
Title: Abscisic acid (ABA) receptors: light at the end of the tunnel Authors
|Muschietti, Jorge -|
Submitted to: Faculty of 1000 Biology
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: December 8, 2009
Publication Date: February 24, 2010
Repository URL: http://f1000biology.com/reports/10.3410/B2-15/article-short.html
Citation: Muschietti, J., Mccormick, S.M. 2010. Abscisic acid (ABA) receptors: light at the end of the tunnel. Faculty of 1000 Biology. 2:15 (doi: 10.3410/B2-15). Interpretive Summary: This review provides an overview of several recent reports in which the abscisic acid receptor was identified and its crystal structure determined.
Technical Abstract: The plant hormone abscisic acid (ABA) plays a role in several aspects of plant growth and development. Understanding how this hormonal stimulus is sensed and transduced turned out to be one of the major tasks in the field of plant signaling. A series of recent papers proposed several different proteins that could receive the ABA signal and initiate the signaling cascade. The winner appears to be PYR/PYL/RCAR (PYrabactin Resistance/ PYrabactin Resistance-Like/Regulatory Component of Abscisic acid Receptor) proteins, as crystal structures were recently published. The crystal structures support the idea that upon ABA binding to a PYR/PYL/RCAR protein, the activity of a phosphatase 2C, with known repressive activity on ABA signaling, is inhibited.