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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Ruminant Diseases and Immunology Research » Research » Publications at this Location » Publication #250551
Title: Control of Bovine Viral Diarrhea Virus in Ruminants

Author
item WALZ, PAUL - Auburn University
item GROOMS, DANIEL - Michigan State University
item PASSLER, THOMAS - Auburn University
item Ridpath, Julia
item TREMBLAY, ROBERT - Boehringer Ingelheim
item STEP, DOUGLAS - Oklahoma State University
item CALLAN, ROBERT - Colorado State University
item GIVENS, M - Auburn University

Submitted to: Journal of Veterinary Internal Medicine
Publication Type: Other
Publication Acceptance Date: 2/24/2010
Publication Date: 6/1/2010
Citation: Walz, P.H., Grooms, D.L., Passler, T., Ridpath, J.F., Tremblay, R., Step, D.L., Callan, R.J., Givens, M.D. 2010. Control of Bovine Viral Diarrhea Virus in Ruminants [ACVIM Consensus Statement]. Journal of Veterinary Internal Medicine. 24(3):476-486.

Interpretive Summary:

Technical Abstract: This document is a consensus statement, produced at the request of the American College of Veterinary Internal Medicine that reflects the opinion of an expert panel regarding the prevalence and host range, clinical manifestations, and the potential for ultimate eradication of bovine viral diarrhea viruses (BVDV). BVDV are viral pathogens that affect multiple organ systems in many ruminant species. BVDV employ multiple strategies to ensure survival and successful propagation in mammalian hosts. These strategies include suppression of the host’s immune system, transmission by various direct and indirect routes, and induction of persistently infected (PI) hosts that shed and transmit BVDV much more efficiently than non-PI animals. Several countries in Europe are nearing completion of BVDV eradication programs. In 2007, the Office of International Epizootics (OIE) added bovine viral diarrhea to its list of reportable diseases of cattle. Successful control of BVDV infections in the United States will require a multidimensional approach, involving vaccination, biosecurity and identification, and elimination of BVDV reservoirs (particularly persistently infected animals).