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Research Project: AFLATOXIN CONTROL THROUGH TARGETING MECHANISMS GOVERNING AFLATOXIN BIOSYNTHESIS IN CORN AND COTTONSEED

Location: Food and Feed Safety Research

Title: Cyclopiazonic Acid Biosynthesis of Aspergillus flavus and Aspergillus oryzae

Authors

Submitted to: Toxins
Publication Type: Review Article
Publication Acceptance Date: November 4, 2009
Publication Date: November 6, 2009
Citation: Chang, P-K., Ehrlich, K., Fujii, I. 2009. Cyclopiazonic Acid Biosynthesis of Aspergillus flavus and Aspergillus oryzae. Toxins. 1:74-99.

Technical Abstract: Cyclopiazonic acid (CPA) is an indole-tetramic acid neurotoxin produced by some of the same strains of A. flavus that produce aflatoxins and by some Aspergillus oryzae strains. Despite its discovery 40 years ago, few reviews of its toxicity and biosynthesis have been reported. This review examines what is currently known about the toxicity of CPA to animals and humans, both by itself or in combination with other mycotoxins. The review also discusses CPA biosynthesis and the genetic diversity of CPA production in A. flavus/oryzae populations.

   

 
Project Team
Bhatnagar, Deepak
Brown, Robert
Chang, Perng Kuang
Yu, Jiujiang
Cary, Jeffrey
Rajasekaran, Kanniah - Rajah
Moore, Geromy
Ehrlich, Kenneth
 
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Related National Programs
  Food Safety, (animal and plant products) (108)
 
 
Last Modified: 05/19/2013
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