Author
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Day, James |
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Zsak, Laszlo |
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Submitted to: Virology
Publication Type: Peer Reviewed Journal Publication Acceptance Date: 12/12/2009 Publication Date: 1/25/2010 Citation: Day, J.M., Zsak, L. 2010. Determination and analysis of the full-length chicken parvovirus genome. Virology. 399(1):59-64. Interpretive Summary: Viral enteric disease in poultry is an ongoing problem in many parts of the world. Many enteric viruses have been identified in turkeys and chickens, including avian astroviruses, rotaviruses, reoviruses, and coronaviruses. Through the application of a molecular screening method to detect novel viral nucleic acid, we recently described the detection and partial characterization of a novel enteric parvovirus in chickens. Subsequent surveys of turkey and chicken flocks in the United States revealed widespread occurrence of parvovirus in poultry. Here we report the first full genome sequence of a novel chicken parvovirus (ChPV). This full genome sequence will prove useful in further investigations into the role that ChPV may play in the poultry enteric disease syndromes. Technical Abstract: Viral enteric disease in poultry is an ongoing problem in many parts of the world. Many enteric viruses have been identified in turkeys and chickens, including avian astroviruses, rotaviruses, reoviruses, and coronaviruses. Through the application of a molecular screening method targeting particle-associated nucleic acid (PAN), we recently described the detection and partial characterization of a novel enteric parvovirus in chickens. Subsequent surveys of intestinal homogenates from turkeys and chickens in the United States revealed widespread occurrence of parvovirus in poultry. Here we report the first full genome sequence of a novel chicken parvovirus, ChPV ABU-P1. ChPV ABU-P1 genome organization, predicted amino acid sequence, and phylogenetic relationships with other described parvoviruses are discussed. |
