ARS | Publication request: Benefits from Cooperation in Genomics

Submitted to: Interbull Annual Meeting Proceedings
Publication Type: Proceedings
Publication Acceptance Date: December 28, 2008
Publication Date: January 28, 2009
Citation: Van Raden, P.M., Wiggans, G.R., Van Tassell, C.P., Sonstegard, T.S., Schenkel, F. 2009. Benefits from Cooperation in Genomics. Interbull Annual Meeting Proceedings. Uppsala, Sweden, Jan. 28–29, 6 pp.

Technical Abstract: Accurate estimation of small genetic effects requires very large data sets. Therefore, benefits from combining data across countries are much larger for genotypes than for phenotypes. Methods of data exchange are compared. Gains in reliability from North American data are much larger using 5,369 Holsteins than 1,361 Jerseys or 228 Brown Swiss. Reliability for young animals increased to >80% using genotypes of 40,000 proven bulls in simulation. Use of 100,000 instead of 50,000 markers improved reliability only 2%. Computer programs may apply very widely because marker inheritance is the same across many species.