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United States Department of Agriculture

Agricultural Research Service

Research Project: GENETIC MECHANISMS AND MOLECULAR GENETIC RESOURCES FOR MAIZE

Location: Plant Genetics Research

Title: Big Data: The Future of Biocuration

Authors
item Howe, Doug - UNIVERSITY OF OREGON
item Costanzo, Maria - STANFORD UNIVERSITY
item Fey, Petra - NORTHWESTERN UNIVERSITY
item Gojobori, Takashi - DDBJ, MISHIMA, JAPAN
item Hannick, Linda - J CRAIG VENTNER INSTITUTE
item Hide, Winston - UNIV OF WESTERN CAPE, SA
item Hill, David - JACKSON LAB BAR HARBOR ME
item Kania, Renate - EMBL, HEIDELBERG GERMANY
item Schaeffer, Mary
item St. Pierre, Susan - HARVARD UNIVERSITY
item Twigger, Simon - MED COLLEGE OF WISCONSIN
item White, Owen - UNIV OF MARYLAND-BALTIMOR
item Rhee, Seung - CARNEGIE INSTITUTE

Submitted to: Nature
Publication Type: Other
Publication Acceptance Date: July 15, 2008
Publication Date: September 4, 2008
Citation: Howe, D., Costanzo, M., Fey, P., Gojobori, T., Hannick, L., Hide, W., Hill, D.P., Kania, R., Schaeffer, M.L., St. Pierre, S., Twigger, S., White, O., Rhee, S.Y. 2008. Big Data: The Future of Biocuration. Nature. 455(7209):47-50.

Technical Abstract: This report is a white paper that describes the roles of biocurators in linking biologists to their data. Roles include: to extract knowledge from published papers; to connect information from different sources in a coherent and comprehensible way; to inspect and correct automatically predicted gene structures and protein sequence to provide high-quality proteomes; to develop and manage structured controlled vocabularies that are crucial for data relations and the logical retrieval of large data sets; to integrate knowledge bases to represent complex systems such as metabolic pathways and protein-interaction networks; to correct inconsistencies and errors in data representation; to help data users to render their research more productive in a timely manner; to steer the design of web-based resources; and to interact with researchers to facilitate direct data submissions to databases.

Last Modified: 10/1/2014
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