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Title: Construction of a fowl adenovirus recombinant to express avian metapneumovirus glycoprotein

Author
item Strother, Keith
item Yu, Qingzhong
item Kapczynski, Darrell
item NAGY, EVA - ONTARIO VET COLL-CANADA
item Zsak, Laszlo

Submitted to: American Veterinary Medical Association Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 12/19/2007
Publication Date: 7/19/2008
Citation: Strother, K.O., Yu, Q., Kapczynski, D.R., Nagy, E., Zsak, L. 2008. Construction of a fowl adenovirus recombinant to express avian metapneumovirus glycoprotein [abstract]. American Association of Avian Pathologists Annual Convention, July 19-23, 2008, New Orleans, Louisiana. 2008 CDROM.

Interpretive Summary:

Technical Abstract: Avian metapneumovirus (aMPV) is the cause of severe respiratory infection in turkeys. Despite detailed sequence analyses of most of the aMPV genes, very little is known about the role these proteins in viral virulence, pathogenesis, and immune response. Here, we report the construction of an avian adenovirus recombinant expressing the aMPV subtype C glycoprotein G gene. This live expression vector will be a valuable tool to study the function of the G gene during virus infection.