Technical Abstract: The catfish aquaculture industry is hampered by off-flavor events that affect timely sale and pond restocking. In this study, weather data was correlated with geosmin and 2-methylisoborneol levels in 21 commercial ponds. Samples were collected weekly for 44 weeks. The off-flavor compounds, geosmin and 2-methylisoborneol, were quantified using gas chromatography-mass spectrometry. Weather data was collected near the catfish farm; and included maximum and minimum air temperature, rainfall, average wind velocity, maximum and minimum humidity, and maximum and minimum soil temperature. Geosmin was weakly and positively correlated with air and soil temperatures, and weakly and negatively correlated with wind velocity and maximum humidity. Conversely, 2-methlisoborneol was strongly and positively correlated with air and soil temperatures, moderately and negatively correlated with wind velocity, and weakly and positively correlated with rainfall and maximum humidity. There were no bivariate relationships between rainfall, minimum humidity, or pond size and levels of either off-flavor compound.