Submitted to: Research Workers in Animal Diseases Conference Proceedings
Publication Type: Abstract Only
Publication Acceptance Date: October 12, 2007
Publication Date: December 2, 2007
Citation: Lillehoj, H.S., Hong, Y. 2007. U.S. Veterinary Immune Reagents Network: progress with poultry immune reagents. [abstract]. Research Workers in Animal Diseases Conference, Chicago, IL, 12/02-04/2007.
A major obstacle to advances in veterinary immunology and disease control is the lack of sufficient immunological reagents specific for ruminants, swine, poultry, equine and aquaculture species. Sets of reagents, i.e., monoclonal (mAb) and polyclonal antibodies, that can identify the major leukocyte subsets (T and B lymphocytes, NK cells, macrophages, dendritic cells, neutrophils) are needed to evaluate changes during disease and following vaccination and to give scientists the ability to manipulate these cell populations in order to evaluate their roles in protective immunity as well as in immunopathology. This poster will describe a new CSREES NRI-funded project to develop above reagents which represents a broad community plan to begin to systematically address the immunological reagent gap for the US veterinary immunology research community, including the following groups: ruminants (concentrating on cattle), swine, poultry (primarily chickens with some evaluation of reagents on turkey cells), horses and aquaculture species (concentrating on channel catfish and salmonid trout-two of the principal economically important species) with a goal of 20 reagents per species group. This poster will update progress with poultry reagents. (This project was supported, in part, by the National Research Initiative of the USDA, U.S. Veterinary Immune Related Reagent Network Grant #2005-01812.