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United States Department of Agriculture

Agricultural Research Service

Title: Measuring vitamins and minerals in dietary supplements for nutrition studies in the USA

Authors
item Dwyer, Johanna - ODS-NIH
item Holden, Joanne
item Andrews, Karen - JOHNS HOPKINS UNIV
item Roseland, Janet
item Zhao, Cuiwei - JOHNS HOPKINS UNIV
item Schweitzer, Amy - JOHNS HOPKINS UNIV
item Perry, Charles - NASS
item Harnly, James
item Wolf, Wayne
item Picciano, Mary Frances - ODS-NIH
item Fisher, Kenneth - ODS-NIH
item Saldanha, Leila - ODS-NIH
item Yetley, Elizabeth - ODS-NIH
item Betz, Joseph - ODS-NIH
item Coates, Paul - ODS-NIH
item Milner, John - NIH
item Whitted, Jackie - NIH
item Burt, Vicki - NIH
item Radimer, Kathy - NIH
item Wilger, Jamie - NIH
item Sharpless, Katherine - NIH
item Hardy, Constance - NIH

Submitted to: Analytical and Bioanalytical Chemistry
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: June 21, 2007
Publication Date: September 20, 2007
Citation: Dwyer, J., Holden, J.M., Andrews, K., Roseland, J.M., Zhao, C., Schweitzer, A., Perry, C., Harnly, J.M., Wolf, W.R., Picciano, M., Fisher, K., Saldanha, L., Yetley, E., Betz, J., Coates, P., Milner, J., Whitted, J., Burt, V., Radimer, K., Wilger, J., Sharpless, K., Hardy, C. 2007. Measuring vitamins and minerals in dietary supplements for nutrition studies in the USA. Analytical and Bioanalytical Chemistry. 389(1):37-46.

Interpretive Summary: This article illustrates the importance of having analytical data for vitamins and minerals in dietary supplements for nutrition studies. Reasons for concern about measuring micronutrients in dietary supplements are reviewed. An analytically validated dietary supplement ingredient database (DSID) for vitamins and minerals developed by a consortium of federal agencies is described. Preliminary studies of multi-vitamin mineral supplements (MVMs) marketed in the U.S. that were analyzed as candidates for the DSID are summarized. Challenges in developing the DSID are described and possible future directions are outlined. Some related programs of the Office of Dietary Supplements (ODS), National Institutes of Health (NIH) in the USA are summarized.

Technical Abstract: This article illustrates the importance of having analytical data on the vitamin and mineral content of dietary supplements in nutrition studies and describes efforts to develop an analytically validated dietary supplement ingredient database (DSID) by a consortium of federal agencies in the USA. Preliminary studies of multi-vitamin mineral supplements marketed in the USA that were analyzed as candidates for the DSID are summarized. Challenges are summarized, possible future directions are outlined, and some related programs at the Office of Dietary Supplements, National Institutes of Health are described. The DSID should be helpful to researchers in assessing relationships between intakes of vitamins and minerals and health outcomes.

Last Modified: 7/30/2014