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United States Department of Agriculture

Agricultural Research Service

Title: Compositions and Methods for the Control, Prevention, and Treatment of Obesity and Eating Disorders

Authors
item Weyer, Christian - AMYLIN PHARMACEUTICALS
item Laugero, Kevin
item Mack, Christin - AMYLIN PHARMACEUTICALS
item Parkes, David - AMYLIN PHARMACEUTICALS

Submitted to: Invention Report
Publication Type: Other
Publication Acceptance Date: January 20, 2006
Publication Date: October 5, 2006
Citation: Weyer, C., Laugero, K.D., Mack, C.M., Parkes, D.G. Compositions and Methods for the Control, Prevention, and Treatment of Obesity and Eating Disorders. Invention Report.

Interpretive Summary: We have discovered a variety of methods and compositions useful in the control, treatment and prevention of obesity, eating disorders, and related conditions and disorders. In a one aspect, methods are provided for the reducing weight in a subject desirous of or in need thereof and the treatment or prevention conditions associated with weight loss, such as alteration of metabolic rates and thermogenesis. In another aspect, methods are provided for reducing weight in a morbidly obese subject, comprising administering an effective amount of amylin or amylin agonist. Also provided are methods for reducing bone loss associated with bariatric surgery. In another aspect, methods are provided for controlling, preventing or treating conditions or disorders associated with eating, such as binge eating, food cravings, and food-related stress disorders.

Technical Abstract: Compositions and methods for preventing, treating or controlling conditions or disorders associated with obesity, diet, and nutrition are provided. The methods provided generally involve the administration of an amylin or an amylin agonist to a subject in order to prevent, treat or controlling conditions or disorders associated with obesity, diet, and nutrition.

Last Modified: 8/30/2014
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