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United States Department of Agriculture

Agricultural Research Service

Research Project: MOLECULAR CHARACTERIZATION OF PATHOGENS AND THEIR RESPONSES TO ENVIRONMENTAL FACTORS Title: Extraintestinal Pathogenic Escherichia Coli (Expec)

Authors
item Smith, James
item Smith, James
item Fratamico, Pina
item Gunther, Nereus

Submitted to: Foodborne Pathogens and Disease
Publication Type: Review Article
Publication Acceptance Date: March 19, 2007
Publication Date: May 31, 2007
Citation: Smith, J.L., Fratamico, P.M., Gunther, N.W. 2007. Extraintestinal pathogenic escherichia coli (expec). Foodborne Pathogens and Disease. Vol.4(2):134-163

Technical Abstract: Extraintestinal pathogenic Escherichia coli (ExPEC) possess virulence traits that allow them to invade, colonize, and induce disease in bodily sites outside of the gastrointestinal tract. Human diseases caused by ExPEC include urinary tract infections, neonatal meningitis, sepsis, pneumonia, surgical site infections, as well as infections in other extraintestinal locations. ExPEC-induced diseases represent a large burden in terms of medical costs and productivity losses. In addition to human illnesses, ExPEC strains also cause extraintestinal infections in domestic animals and pets. A commonality of virulence factors has been demonstrated between human and animal ExPEC suggesting that the organisms are zoonotic pathogens. ExPEC strains have been isolated from food products, in particular from raw meats and poultry, indicating that these organisms potentially represent a new class of foodborne pathogens.

Last Modified: 12/21/2014
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