Submitted to: American Chemical Society Symposium Series
Publication Type: Book / Chapter
Publication Acceptance Date: March 22, 2007
Publication Date: November 1, 2008
Citation: Appell, M.D., Maragos, C.M., Kendra, D.F. 2008. Molecularly Imprinted Polymers for Mycotoxins. American Chemical Society Symposium Series. 1001:152-169. Interpretive Summary: Mycotoxins are natural contaminants of agricultural commodities that are a source of economic loss and capable of harming humans and animals. Mycotoxin detection can be aided by the development of new materials to recognize mycotoxins. Molecularly imprinted polymers are synthetic polymers capable of recognition. Recent reports of molecularly imprinted polymers for mycotoxins are reviewed. Further investigations of the application of a molecularly imprinted polymer for moniliformin are presented.
Technical Abstract: Molecularly imprinted polymers (MIPs) are a class of synthetic receptors capable of selective recognition of analytes. Recent developments in imprinting technology have made it possible to apply this technology in a range of applications, including mycotoxin detection. Structure-activity relationships between reported MIPs for ochratoxin A, deoxynivalenol and zearalenone are reviewed. In addition, results from a molecular imprinted solid phase extraction (MISPE) analysis of MIPs designed to recognize moniliformin show the binding properties of the moniliformin MIPS are influenced by solvent and matrix effects.