ARS | Publication request: Supported Phospholipid Bilayer Defects Created by a Cation or Anion of a Room-Temperature Ionic Liquid

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: August 8, 2006
Publication Date: August 8, 2006
Citation: Evans, K.O., Hawkins, G. 2006. Supported phospholipid bilayer defects created by a cation or anion of a room-temperature ionic liquid [abstract]. American Chemical Society Project SEED Poster Session, Illinois State University. Abstract 1.

Technical Abstract: In this work, the independent effects on a supported phospholipid bilayer (SPB) caused by a cation and anion of a room-temperature ionic liquid (RT-IL) were studied via atomic force microscopy (AFM). The supported phospholipid bilayer was composed only of 1,2-dielaidoylphosphatidylcholine (DEPC) and formed onto silica wafers. When the supported phospholipid bilayer was exposed to 1-octyl-3-methyl imidazolium (OMIM+, a RT-IL cation) chloride, the SPB developed defects where the bilayer was swollen and/or partially removed. The severity of these defects was dependent upon exposure time to OMIM+ (the longer the exposure, the greater the defect observed). When the SPB was exposed to lithium bis(trifluoromethylsulfonyl)imide (Tf2N-, a RT-IL anion), defects with pore-like structures formed. AFM observations substantiate the implications made from fluorescence measurements [Evans, K.O. 2006. Colloids and Surfaces A: Physicochemical Engineering Aspects 274:11–17].