ARS | Publication request: Identification of two genotype subgroups of porcine circovirus type 2 in swine herds of the United States

Submitted to: Research Workers in Animal Diseases Conference Proceedings
Publication Type: Abstract Only
Publication Acceptance Date: December 3, 2006
Publication Date: December 3, 2006
Citation: Cheung, A.K., Lager, K.M., Vincent, A.L. 2006. Identification of two genotype subgroups of porcine circovirus type 2 in swine herds of the United States [abstract]. Conference of Research Workers in Animal Diseases 87th Annual Meeting. Paper No. 171. p. 78.

Technical Abstract: Sporadic cases of high mortality postweaning multisystemic wasting syndrome (PMWS) were observed in 10- to 16-week-old growing pigs among several swine herds of the United States in late 2005. Porcine circovirus type 2 (PCV2) was consistently detected in the affected pigs from Kansas, Iowa, and North Carolina. Phylogenetic analysis demonstrated that the majority of the viral sequences present in these PMWS-associated pigs have never been reported (GenBank as of May 16, 2006) in the United States or in Canada before. Interestingly, these new sequences are closely related to the virus isolates that have been previously reported in Europe and Asia. The data showed that PCV2 can be separated into two genotype subgroups with each subgroup containing a conserved signature motif sequence in the capsid gene.