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United States Department of Agriculture

Agricultural Research Service

Research Project: MOLECULAR ANALYSIS OF VIRULENCE DETERMINANTS OF SELECT BACTERIA IN FISH DISEASES Title: Vaccines to Prevent Streptococcus Iniae and S. Agalactiae Disease in Tilapia Oreochromis Niloticus

Authors
item Klesius, Phillip
item Evans, Joyce
item Shoemaker, Craig
item Pasnik, David

Submitted to: International Symposium on Talipia in Aquaculture
Publication Type: Abstract Only
Publication Acceptance Date: July 13, 2006
Publication Date: September 6, 2006
Citation: Klesius, P.H., Evans, J.J., Shoemaker, C.A., Pasnik, D.J. 2006. Vaccines to prevent Streptococcus iniae and S. agalactiae disease in tilapia Oreochromis niloticus. 7th International Symposium on Tilapia in Aquaculture. Talk/Abstract. September 6-8, 2006. Veracruz, Mexico.

Technical Abstract: Minimizing the effects of diseases is crucial to prevent mortality, morbidity, and to promote optimal growth and feed conversion in sustained culture of warm-water fish in fresh, estuarine and marine waters. The control of diseases has been dependent on the use of therapeutics since the inception of aquaculture. The resolute demands of consumers, environmental and governmental groups for wholesome fish and for an environment free of potentially harmful drugs in aquaculture production have increased. In addition, issues related to increased emergence of antibiotic resistant pathogens have made headlines and stimulated serious public concern. The continued growth and well-being of the aquaculture industry requires that the industry meet the challenges for minimizing the effects of disease and provide a wholesome product, while preventing further development in pathogen resistance to antibiotics and chemotherapeutics. The aquaculture industry can meet these challenges with more rapid and expanded health management practices that make use of vaccines to increase survival, optimal growth, and feed conversion of farmed fish. Vaccination is among the most successful veterinary practices to prevent deaths and to provide animal production and biosecurity safeguards. In recent years, fish vaccinology has made real progress in both the safety and efficacy of the vaccines, especially against bacterial diseases of salmonids. However, very limited information is available in the literature on vaccination of tilapia against streptococcal pathogens. Streptococcus iniae and S. agalactiae have been recognized as emerging pathogens that are highly virulent for a many species of cultured fish. The economic impact of S. iniae and S. agalactiae to the aquaculture industry is estimated in hundreds of millions annually, worldwide. This presentation will focus on the development of vaccines against S. iniae and S. agalactiae and the strategies and benefits of the vaccination of tilapia in preventing streptococcosis. Results will be presented that demonstrate the efficacy of these vaccines after injection and bath immersion of tilapia and at targeted life stages.

Last Modified: 10/22/2014
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