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Research Project:
AQUATIC ANIMAL DIAGNOSTICS, PATHOGENESIS AND APPLIED EPIDEMIOLOGY
Location: Aquatic Animal Health Research
Title: METHOD OF PROTECTING FISH AGAINST COLUMNARIS DISEASE WITH MODIFIED LIVE FLAVOBACTERIUM COLUMNARE
Authors
Submitted to: Invention Report
Publication Type: Patent Application
Publication Acceptance Date: January 31, 2006
Publication Date: January 31, 2006
Citation: Shoemaker, C.A., Klesius, P.H., Evans, J.J. 2006. Method of protecting fish against columnaris disease with modified live Flavobacterium columnare. U.S. Patent US 6,991,793 B2.
Technical Abstract:
Safe and effective live vaccines against Flavobacterium columnare of fish were created through the induction of rifampicin resistance in a native Flavobacterium columnare isolate; these including rifampicin-resistant mutants NRRL B-30303 and B30304. Single immersion exposure of fish stimulated acquired immunity against virulent F. columnare infection.
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Last Modified: 05/21/2013
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