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United States Department of Agriculture

Agricultural Research Service

Title: An Integrated Bac Physical Map of the Pig Genome and Selection of the Minimum Tilepath

Authors
item Humphray, Sean - SANGER INST, CAMBRIDGE UK
item Scott, Carol - SANGER INST, CAMBRIDGE UK
item Clark, Richard - SANGER INST, CAMBRIDGE UK
item Marron, Brandy - UNIV ILLINOIS, URBANA
item Plumb, Robert - SANGER INST, CAMBRIDGE UK
item Rogatcheva, Margarita - UNIV ILLINOIS, URBANA
item Milan, Denis - INRA, TOLOSAN, FRANCE
item Chardon, Patrick - INRA, JOUY EN JOSAS, FRAN
item Rohrer, Gary
item Nonneman, Danny
item DE Jong, Pieter - BACPAC RESOURCES, OAKLAND
item Meyers, Stacy - UNIV ILLINOIS, URBANA
item Bender, Clare - SANGER INST, CAMBRIDGE UK
item Archibald, Alan - ROSLIN INST, ROSLIN, UK
item Beever, Jonathon - UNIV ILLINOIS, URBANA
item Schook, Lawrence - UNIV ILLINOIS, URBANA
item Rogers, Jane - SANGER INST, CAMBRIDGE UK

Submitted to: Plant and Animal Genome Conference Proceedings
Publication Type: Abstract Only
Publication Acceptance Date: December 1, 2005
Publication Date: January 14, 2006
Citation: Humphray, S., Scott, C., Clark, R., Marron, B., Plumb, R., Rogatcheva, M., Milan, D., Chardon, P., Rohrer, G.A., Nonneman, D.J. 2006. An integrated BAC physical map of the pig genome and selection of the minimum tilepath. Plant and Animal Genome Conference Proceedings. Poster #W237. p. 60.

Interpretive Summary: No interpretive summary required.

Technical Abstract: We have constructed a physical map of the pig genome by integrating restriction fingerprints and BAC end sequences generated from 4 BAC libraries with radiation hybrid markers, and contig alignments to the human genome. The map provides coverage across the 18 pig autosomes and the X chromosome in 176 contigs as well as localised representation of the gene rich regions on Y. The map is accessible through WebFPC (http://www.sanger.ac.uk/Projects/S_scrofa/WebFPC/porcine/large.shtml) and represents an entry point for rapid electronic positional cloning of genes and fine mapping of QTLs. The map provides a platform for the selection of an efficient minimum tilepath through the genome to support clone-based sequencing and targeted functional genomics studies.

Last Modified: 10/21/2014