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United States Department of Agriculture

Agricultural Research Service

Title: Ultrasensitive Immunoassays Based on Surface-Enhanced Raman Scattering by Immunogold Labels

Authors
item Park, Hye-Young - IOWA STATE UNIVERSITY
item Driskell, Jeremy - IOWA STATE UNIVERSITY
item Kwarta, Karen - IOWA STATE UNIVERSITY
item Lipert, Robert - IOWA STATE UNIVERSITY
item Porter, Marc - IOWA STATE UNIVERSITY
item Schoen, Christian - CONCURRENT ANALYTICAL INC
item Neill, John
item Ridpath, Julia

Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: February 11, 2006
Publication Date: September 21, 2006
Citation: Park, H., Driskell, J.D., Kwarta, K.M., Lipert, R.J., Porter, M.D., Schoen, C., Neill, J.D., Ridpath, J.F. 2006. Ultrasensitive Immunoassays Based on Surface-Enhanced Raman Scattering by Immunogold Labels. In: Kneipp, K., Moskovits., M., Kneipp, H., editors. Surface-Enhanced Raman Scattering - Physics and Applications, Topics in Applied Physics. Berlin/Heidelberg: Springer-Verlag. 103:427–446.

Technical Abstract: This chapter describes recent advances in the use of surface-enhanced Raman Scattering (SERS) as a readout tool for chip-scale, sandwich-based immunoassays. It reviews progress made in developing SERS-based immunoassays for a wide range of biolytes, including proteins, viruses and bacteria. The studies reviewed herein demonstrate that SERS-based immunoassay have the potential to serve as the cornerstone for a highly sensitive, high throughput bioanalytical methodology.

Last Modified: 11/28/2014
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