Technical Abstract: Weeds reduce potato yield and quality and require management in all cropping systems. Weeds can be best managed using an integrated weed management approach that involves field selection and crop rotation, monitoring and field surveys, sanitation of equipment, and proper integration of cultivation and herbicides. Herbicide carryover, managing herbicide resistant weeds, and soil testing are components of weed management requiring careful attention of crop managers. Common weeds of potato rotations, their biology and identification, and control options are discussed in this chapter intended for potato growers and crop managers.