ARS | Publication request: PROTECTION AGAINST CAO2ENDV CHALLENGE OF CHICKENS VACCINATED WITH INACTIVATED VACCINES OF NEWCASTLE DISEASE VIRUS (NDV) FROM DIFFERENT GENETIC LINEAGES

Submitted to: American Association of Avian Pathologists
Publication Type: Abstract Only
Publication Acceptance Date: January 18, 2006
Publication Date: July 16, 2006
Citation: Miller, P.J., King, D.J., Suarez, D.L. 2006. Protection against CAO2ENDV challenge of chickens vaccinated with inactivated vaccines of Newcastle disease virus (ndv) from different genetic lineages [abstract]. American Association of Avian Pathologists. CD p. 157.

Technical Abstract: A comparison of the serological response and protection induced by vaccines prepared from NDV strains that represent genetically diverse isolates of the avian paramyxovirus type 1 serotype was made. Four-week-old leghorns were vaccinated with one of six different BPL inactivated vaccines; B1, Ulster, CA 2002ENDV, Pigeon 84, Alaska 196 and a normal allantoic fluid control vaccine. Three weeks post vaccination, serum was collected for antibody analysis and the birds were challenged with the velogenic strain, CA2002 ENDV. The birds were examined daily and were monitored for virus shedding at regular intervals. All vaccines except for the allantoic fluid control induced greater than 90% protection to clinical disease. Further analysis among vaccines will be presented.