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United States Department of Agriculture

Agricultural Research Service

Title: Effect of Sodium [36cl]chlorate Dose on Total Radioactive Residues and Residues of Parent Chlorate in Swine.

Authors
item Smith, David
item Anderson, Robin

Submitted to: Meeting Proceedings
Publication Type: Proceedings
Publication Acceptance Date: July 7, 2005
Publication Date: September 6, 2005
Citation: Smith, D.J., Anderson, R.C. 2005. Effect of sodium [36Cl]chlorate dose on total radioactive residues and residues of parent chlorate in swine. Proceedings of the 6th International Symposium on the Epidemiology & Control of Foodborne Pathogens in Pork (SafePork 2005), Sept. 6-9, 2005, Rohnert Park, CA, pp. 142-144.

Technical Abstract: Sodium chlorate effectively reduces the numbers of gram-negative pathogens in gastrointestinal tracts of live animals when administered in the 24 to 72 hour period prior to slaughter. It is believed that a chlorate-based product could be a cost-effective and efficient method to reduce the contamination of carcasses during animal processing. The purpose of this study was to determine a dose of sodium chlorate in swine that would result in chlorate residues below FDA CVM-estimated safe tissue concentrations. Three sets of swine (one barrow and one gilt each) were dosed with 20, 40, or 60 mg/kg sodium [36Cl]chlorate dissolved in drinking water during a 24-hour exposure period. Animals were slaughtered after a 24-hour withdrawal period and edible tissues were removed and analyzed for chlorate content. Total radioactive residues and chlorate residues in edible tissues and excreta of swine will be reported.

Last Modified: 7/23/2014