|Hanner, Robert - UNIV OF GUELPH ONTARIO, C|
Submitted to: Trade Journal Publication
Publication Type: Review Article
Publication Acceptance Date: September 1, 2005
Publication Date: May 1, 2006
Citation: Walters, C., and Hanner, R. 2006. Platforms for DNA Banking. p. 25-35. In M. Carmen de Vicente and Meike S. Andersson (eds.) Issues in Genetic Resources DNA Banks - Providing Novel Options for Genebanks? International Plant Genetic Resources Institute, Rome, Italy. Interpretive Summary: A DNA bank is a particular type of genetic resource bank that preserves and distributes the DNA molecule and provides associated information. Existing DNA banks usually support human medical applications, but may also be necessary to support genomic projects in all species. This paper summarizes information on different strategies to bank DNA.
Technical Abstract: The accelerated use of genomic technology in biological research portends a changing pattern in the use of genetic resource collections and fuels the desire among researchers to establish DNA banks. DNA sequencing of herbarium sheet specimens, cell cultures and germplasm offers a new approach to studies of gene function, evolution, taxonomy and epidemiology among plants. A catalog of unique genetic sequences or “DNA barcodes” can conceptually unite diverse assemblages of repositories under a common registry of sequence accessions. The challenge for DNA repositories of today is to provide a product that is amenable for uses anticipated in the future. Long-term needs will have a decisive impact on operational organization and repository design and a major limitation involves specimen quality and shelf-life.