ARS | Publication request: PROGRESS ON THE DEVELOPMENT OF MOLECULARLY IMPRINTED POLYMERS FOR MYCOTOXINS

Submitted to: Association of Analytical Communities International Midwest Section
Publication Type: Abstract Only
Publication Acceptance Date: May 26, 2005
Publication Date: May 26, 2005
Citation: Maragos, C.M., Appell, M.D. 2005. Progress on the development of molecularly imprinted polymers for mycotoxins [abstract]. Association of Analytical Communities International Meeting Midwest Section. Book of Abstracts. p. 36.

Technical Abstract: Because they are small molecules that are found in foods at low levels, mycotoxins must generally be extracted from foods or feeds before quantitation. For this reason, materials that bind mycotoxins are useful in isolating these toxins from foods. However, they can also be used in protecting domestic animals from toxin exposure, and as components of test kits for mycotoxin detection. Examples of mycotoxin-binding materials are plentiful and range from natural materials such as aluminosilicates and antibodies to man-made materials such as molecularly imprinted polymers (MIPs). Recently MIPs have been described in the literature for deoxynivalenol, zearalenone, and the ochratoxins. These reports and the design and synthesis of MIPs for moniliformin and patulin have lead to insights into the application of this approach to the generation of mycotoxin binding materials. In particular the rational design of polymers can be aided by the evaluation of potential functional monomers and templates using computational approaches. Continued development of improved mycotoxin-binding materials will prove relevant to future detection strategies for these toxins in foods.