Page Banner

United States Department of Agriculture

Agricultural Research Service

Title: The Effect of An Experimental Chlorate Compound on Salmonella Recovery of Turkeys When Administered Prior to Feed and Water Withdrawal

Authors
item Moore, Randle
item BYRD, JAMES
item Knape, K - TEXAS A&M UNIV
item ANDERSON, ROBIN
item CALLAWAY, TODD
item EDRINGTON, THOMAS
item Kubena, Leon
item NISBET, DAVID

Submitted to: Poultry Science
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: March 23, 2006
Publication Date: December 1, 2006
Citation: Moore, R.W., Byrd Ii, J.A., Knape, K.D., Anderson, R.C., Callaway, T.R., Edrington, T.S., Kubena, L.F., Nisbet, D.J. 2006. The effect of an experimental chlorate compound on salmonella recovery of turkeys when administered prior to feed and water withdrawal. Poultry Science.

Interpretive Summary: Chlorate compounds have been used for some time to reduce bacterial numbers and recently they have been used to reduce infectious pathogens in chickens and pigs. This study was performed to evaluate an experimental chlorate compound on Salmonella infections in Market aged turkeys. Two experiments were performed were several concentrations of the experimental chlorate product was administered to market aged turkeys for various durations in the drinking water. The turkeys were administered Salmonella prior to and during treatment, and after treatment, crop and ceca organs were collected and cultured for Salmonella. For all treatment concentrations and durations, the experimental chlorate product significantly reduced the number of Salmonella recovered from crops and ceca. These experiments suggest that the experimental chlorate product may reduce Salmonella colonization in commercial turkeys when administered prior to market processing.

Technical Abstract: Previously, chlorate compounds have been observed to reduce E. coli and Salmonella infections in swine and broilers. The following studies were performed to investigate the effects of an experimental chlorate product on Salmonella typhimurium (ST) infections of turkeys. Two experiments were performed to investigate the effect of concentration and duration of the experimental product on crop and ceca Salmonella recovery. In all trials for Experiment 1, 15 week-old turkey toms were challenged with 10,000,000 to 100,000,008 cfu of ST and administered either 0 or 0.5x, 1.0x, 2.0x, or 4.0x of the chlorate product (a 1.0x concentration is equivalent to a 15 mM chlorate ion concentration) in the drinking water for 38 h. Treatment was followed by a 10 h water withdrawal and an 8 h feed withdrawal prior to organ sampling. For all treatment concentrations, turkeys provided with the experimental chlorate product had significantly (P<0.05) lower populations and incidences of crop (> 1.4 log reduction) and ceca (> 0.6 log reduction) ST as compared to control birds (2.1 and 0.94 log ST average for all trials, respectively). In all trials for Experiment 2, 15 week-old turkey toms were challenged with 108 to 109 cfu of ST and administered a 2.0x concentration of the chlorate product in the drinking water for either 38 h, 26 h, 14 h, or 0 h prior to water withdrawal. Treatment was followed by a 10 h water withdrawal and an 8 h feed withdrawal prior to organ sampling. For all treatment durations, turkeys provided with the experimental chlorate product had significantly (P<0.05) lower populations and incidences of crop (> 2.2 log reduction) and ceca (> 1.5 log reduction) ST as compared to control birds (3.1 and 1.8 log ST average for all trials, respectively). These experiments suggest that the experimental chlorate compound significantly reduces Salmonella colonization in commercial turkeys when administered prior to feed and water withdrawal.

Last Modified: 9/10/2014