Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: June 28, 2004
Publication Date: June 25, 2005
Citation: Liu, Z., Slininger, P.J. 2005. Development of genetically engineered stress tolerant ethanologenic yeasts using integrated functional genomics for effective biomass conversion to ethanol. In: Collins, K., Duffield, J., Outlaw, J., editors. Agriculture as a Producer and Consumer of Energy. Wallingford, UK: CAB International, p. 283-294.
Inhibitory compounds generated during acid hydrolysis of renewable agricultural biomass interfere with subsequent ethanol fermentation. We elucidate the chemical stress tolerance mechanisms of Saccharomyces cerevisiae using genomic expression analysis; and develop genetically engineered novel ethanologenic strains to detoxify fermentation inhibitors in situ for effective bioethanol production.