Submitted to: Trends in Immunology
Publication Type: Review Article
Publication Acceptance Date: December 30, 2004
Publication Date: February 1, 2005
Citation: De Los Santos, T., Grubman, M.J. 2005. Rapid Control of Foot-and-Mouth Disease: Is RNAi a Possible Solution?. Trends in Immunology 26 (2)P 65-68. Technical Abstract: RNA interference is a mechanism of gene silencing that is being examined as an antiviral strategy in mammalian cells. Chen et al. have utilized this approach to examine its potential against foot-and-mouth disease (FMD), an extremely contagious viral disease of cloven-hoofed animals. This article discusses these experiments and comments on the possible use of RNA interference, as well as other antiviral strategies, as a rapid method of FMD control.