Submitted to: Phytopathology
Publication Type: Abstract Only
Publication Acceptance Date: March 30, 2004
Publication Date: June 30, 2004
Citation: Gildow, F.E., Cox-Foster, D., Gray, S.M. 2004. Cellular and molecular regulation of luteovirus transmission by aphid vectors. Phytopathology. 94:S134.
Luteoviruses replicate only in phloem cells of infected plants and are transmitted by aphids in a vector-specific circulative manner. Although luteoviruses are transported through aphid cells, the viruses are not known to replicate in aphids. Ultrastructural studies identified the mechanisms of luteovirus transport through aphid gut and salivary tissues and indicated that vector-specificity is regulated both at cell membranes and basal lamina. Luteovirus-binding proteins specific to aphid species have been identified. The similarity of virus-binding proteins in aphids transmitting the same luteoviruses suggests a conservation of receptors regulating cell recognition of viruses. Independent genetic studies of vector and nonvector clones of aphids indicate that transmission competency is controlled by different alleles. Current work is directed at identifying genetic components defining vector competence of aphids and characterizing gene products involved in virus recognition and transport in aphids.