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United States Department of Agriculture

Agricultural Research Service

Title: Comparison of the Full Length Genome Sequence of Avian Metapneumovirus Subtype C with Other Paramyxoviruses Including Highly Virulent Newcastle Disease Viruses

Authors
item Lwamba, Humphrey C - UNIV OF MN, ST PAUL, MN
item Alvarez, Rene - CDC, ATLANTA, GA
item Wise, Mark
item Yu, Qingzhong
item Halvorson, David - UNIV OF MN, ST PAUL, MN
item Njenga, M Kariuki - UNIV OF MN, ST PAUL, MN
item Seal, Bruce

Submitted to: Virus Research
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: July 10, 2004
Publication Date: January 1, 2005
Citation: Lwamba, H.M., Alvarez, R., Wise, M., Yu, Q., Halvorson, D., Njenga, M., Seal, B.S.2005. Comparison of the Full Length Genome Sequence of Avian Metapneumovirus Subtype C With Other Paramyxoviruses Including Highly Virulent Newcastle Disease Viruses. Virus Research. 107(1):83-92.

Interpretive Summary: Avian metapneumoviruses (AMPV) cause an upper respiratory tract disease designated turkey rhinotracheitis (TRT). The disease in commercial turkeys does not usually cause death, but symptoms can be more severe when accompanied by secondary bacterial infections. Prior to 1996 the disease was not found in the United States. However, a new viral subtype C different from European subtype A and B viruses is now present among commercial United States turkey flocks. The complete nucleotide sequence for the avian metapneumovirus type C genome was completed by ARS scientists in collaboration with investigators at the University of Minnesota. Based on the full genome sequence we have confirmed that the type C virus now found in the United States is unique among the avian viruses and more closely related to a recently reported metapneumovirus isolated from humans.

Technical Abstract:

Last Modified: 7/24/2014
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