ARS | Publication request: EFFICACY OF A KILLED STREPTOCOCCUS INIAE VACCINE IN TILAPA (OREOCHROMIS NILOTICUS)

Submitted to: European Association of Fish Pathologists
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: January 24, 1999
Publication Date: June 1, 1999
Citation: KLESIUS, P.H., SHOEMAKER, C.A., EVANS, J.J. EFFICACY OF A KILLED STREPTOCOCCUS INIAE VACCINE IN TILAPA (OREOCHROMIS NILOTICUS). EUROPEAN ASSOCIATION OF FISH PATHOLOGISTS. 19(1),39, 1999.

Interpretive Summary: Tilapia (Oreochromis niloticus) were vaccinated intraperitoneally (IP) at mean weights of 25 and 100g with killed Streptococcus iniae vaccine composed of whole cells and concentrated, extracellular products (greater than 2 kDa). At 30 days post vaccination, the groups of vaccinates and non vaccinates were IP challenged and monitored daily for clinical signs and mortality for 60 days. Vaccination reduced mortality 91.3 percent and prevented erratic swimming, hemorrhagic exophthalmia and ocular opacity. Immunized 25g tilapia had relative percent survival (RPS) of 95.3 and 100g tilapia had RPS's ranging from 84.2 to 94.7.

Technical Abstract: Tilapia (Oreochromis niloticus) were vaccinated intraperitoneally (IP) at mean weights of 25 and 100g with killed Streptococcus iniae vaccine composed of whole cells and concentrated, extracellular products (greater than 2 kDa). At 30 days post vaccination, the groups of vaccinates and non vaccinates were IP challenged and monitored daily for clinical signs and mortality for 60 days. Vaccination reduced mortality 91.3 percent and prevented erratic swimming, hemorrhagic exophthalmia and ocular opacity. Immunized 25g tilapia had relative percent survival (RPS) of 95.3 and 100g tilapia had RPS's ranging from 84.2 to 94.7.