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United States Department of Agriculture

Agricultural Research Service

Title: Evaluation of a Novel Approach for Identification of Highly Effective Theraputic and Prophylactic Competetive Exclusion Cultures for Food Borne Pathogens.

Authors
item Donoghue, Dan - UNIV OF ARKANSAS
item Hargis, Billy - UNIV OF ARKANSAS
item Newberry, Lisa - UNIV OF ARKANSAS
item Donoghue, Ann
item Bielke, Lisa - UNIV OF ARKANSAS
item Holliman, J - UNIV OF ARKANSAS
item Blore, P - UNIV OF ARKANSAS
item Wolfenden, A - UNIV OF ARKANSAS

Submitted to: Food Safety Consortium Proceedings
Publication Type: Proceedings
Publication Acceptance Date: September 30, 2003
Publication Date: October 12, 2003
Citation: Donoghue, D.J., Hargis, B.M., Newberry, L.A., Donoghue, A.M., Bielke, L.R., Holliman, J.S., Blore, P.J., Wolfenden, A.D. 2003. Evaluation of a novel approach for identification of highly effective theraputic and prophylactic competetive exclusion cultures for food borne pathogens [CD-ROM]. Version 1. Fayetteville, AR: Food Safety Consortium Proceedings.

Technical Abstract: The intentional early colonization of the intestinal tract with beneficial microflora, known as competitive exclusion, has been shown to successfully protect poultry from selected enteric pathogens. While effective cultures have been produced and are available, an inexpensive, air tolerant and completely defined culture is needed. Presently, we developed an in vitro competition assay to select for individual facultative anaerobes, of poultry enteric origin, that could exclude Salmonella and/or Campylobacter. Using combinations of prebiotics selected to out complete these pathogens in vitro, our laboratories have demonstrated that these relatively simple defined cultures consisting of air-tolerant bacteria can inhibit Salmonella and Camplyobacter colonization in chicks and poults.

Last Modified: 10/20/2014
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