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United States Department of Agriculture

Agricultural Research Service

Title: Structural and functional alterations in major peanut allergens caused by thermal processing.

Authors
item Maleki, Soheila
item Hurlburt, Barry

Submitted to: Journal of Association of Official Analytical Chemists International
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: March 4, 2004
Publication Date: November 10, 2004
Citation: Maleki, S.J., Hurlburt, B.K. 2004. Structural and functional alterations in major peanut allergens caused by thermal processing. Journal of Association of Official Analytical Chemists International. 87(6):1475-1479.

Interpretive Summary: The majority of foods that we eat are subjected to some type of processing, either at home, or by the manufacturer. Specifically, our research focus is about the effects of roasting on the allergenic properties of peanut proteins. Roasting has been shown to alter specific biophysical and immunological properties of peanut proteins, such as; structure, function, solubility, digestibility, IgE binding, and T-cell responses. A better understanding of the effects of thermal-processing-induced biochemical and immunological alterations is of utmost importance for proper risk assessment of existing and newly introduced proteins in the food source, as well as development of effective diagnostic tools and therapeutic treatments for food allergy.

Technical Abstract: The majority of foods that we eat are subjected to some type of processing, either at home or by the manufacturer. Thermal processing can cause biochemical reactions to occur in foods that can be both beneficial and harmful. Here, we briefly review the effects of thermal processing and some of the effects of the Maillard reaction on the allergenicity of food proteins. Specifically, we focus on the known effects of roasting on the allergenic properties of peanut proteins, and the contribution of Maillard reaction products (MRP) or advanced glycation end-products (AGE) to these observed effects. The most thorough understanding of the effects of thermal processing on allergenicity involves the peanut proteins. Thermal processing has been shown to alter specific biophysical and immunological properties of peanut proteins such as structure, function, solubility, digestibility, IgE binding and, T-cell responses. A better understanding of the effects of thermal-processing-induced biochemical and immunological alterations is of utmost importance for proper risk assessment of existing and newly introduced proteins in the food source, as well as development of effective diagnostic tools and therapeutic treatments for food allergy.

Last Modified: 12/20/2014