Submitted to: Journal of Nutrition
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: March 15, 2002
Publication Date: June 26, 2002
Citation: Lifschitz, C.H., Grusak, M.A., Butte, N.F. 2002. Human Nutrition and Metabolism Research Communication: Carbohydrate digestion in humans from a beta-glucan-enriched barley is reduced. Journal of Nutrition. 132:2593-2596. Interpretive Summary: The modified barley studied is less well absorbed and utilized than traditional barley. The modified barley thus could serve as a nutritionally appropriate food item for patients with diabetes or obesity.
Technical Abstract: Obese and diabetic patients may benefit from foodstuffs that are poorly absorbed and/or digested at a slower rate. Prowashonupana (PW) is a cultivar of barley, whose grains are enriched in beta-glucans, and thus may be less digestible than standard barley (barley cultivar (BZ) 594.35.e). To test this, both kinds of barley were grown in a chamber into which (13)CO(2) was injected. On two occasions, 10 healthy hydrogen (H(2))-producing adults consumed in random order one 35-g portion of each of the cooked, dehulled (13)C-enriched grains. CO(2) production was measured in a whole-body direct calorimeter, and H(2) and (13)CO(2) were measured in breath at baseline and intermittently for 450 min. The percentage of the (13)C dose recovered in breath was calculated. Results were compared by repeated measures analysis of variance (ANOVA). The percentage of the (13)C dose oxidized was greater after BZ than after PW consumption (P < 0.05). The area under the curve for H(2) was greater after PW (mean +/- SD, 8658 +/- 6582) than after BZ (5178 +/- 4759) intake (P < 0.05), whereas there was no difference in CO(2) production. We conclude that absorption of PW is significantly lower than that of BZ, making the modified barley appropriate for obese and diabetic patients.