COMPARISON OF MULLTIPLE ANTIMICROBIAL RESISTANCE AMONG SALMONELLA ISOLATES OF ANIMAL ORIGIN

Authors: Cray, Paula; HEADRICK, M - FDA-CVM; SALAMONE, B - USDA-FSIS; ANADARAMAN, N - USDA-FSIS; ROSE, B - USDA-FSIS; Gray, Jeffrey; DARGATZ, D - USDA-APHIS

Submitted to: International Association for Food Protection
Publication Type: Abstract Only
Publication Acceptance Date: 4/1/2003
Publication Date: 6/1/2003
Citation: Cray, P.J., Headrick, M., Salamone, B., Anadaraman, N., Rose, B., Gray, J.T., Dargatz, D.A. 2003. Comparison of mulltiple antimicrobial resistance among salmonella isolates of animal origin. International Association for Food Protection. Abstract# T65. P. 141.

Interpretive Summary:

Technical Abstract: Antimicrobial Resistance Monitoring System - Enteric Bacteria (NARMS) monitors for developing resistance among Salmonella isolates of animal origin, particularly from cattle, chicken, swine and turkey. Salmonella isolates were collected from federally inspected slaughter and processing plants and veterinary diagnostic laboratory submissions. Antimicrobial susceptibility testing was conducted using the Sensititre System (Trek Diagnostics). Seventeen antimicrobials were tested. Data were analyzed for multiple resistance, defined as resistance to greater than or equal to 2 antimicrobials. Overall, slaughter isolates were more susceptible than diagnostic isolates with the exception of isolates collected from chickens. Multiple resistance was observed most often among diagnostic isolates. The top ten serotypes varied widely by year between slaughter and diagnostic isolates for all sources (cattle, chicken, swine and turkey). Additionally, resistance, especially multiple resistance, varied widely among serotypes. Regardless of source, S. Typhimurium was both more resistant and the most multiple resistant serotype. Molecular analysis of multiple resistant cassettes will assist in further defining these isolates. These data indicate that multiple resistance is common among some serotypes of Salmonella.