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United States Department of Agriculture

Agricultural Research Service

Title: The Inhibitory Activity of Natural Products on Plant P-Hydroxyphenyl Pyruvate Dioxygenase

Authors
item Meazza, Giovanni - ISAGRO RICERCA, ITALY
item Scheffler, Brian
item Tellez, Mario
item Rimando, Agnes
item Romagni, Joanne - UNIVERSITY OF MISSISSIPPI
item Duke, Stephen
item Nanayakkara, Dhammika - UNIVERSITY OF MISSISSIPPI
item Khan, Ikhlas - UNIVERSITY OF MISSISSIPPI
item Abourashed, Ehad - UNIVERSITY OF MISSISSIPPI
item Dayan, Franck

Submitted to: Phytochemistry
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: March 5, 2002
Publication Date: June 1, 2002

Interpretive Summary: The enzyme hydroxyphenylpyruvate dioxygenase is a new target site for herbicides. In our search for natural product-based pest management tools, we have discovered that this enzyme is sensitive to a variety of natural compounds. The potential benefit of this research is the development of new 'natural' pesticides.

Technical Abstract: Hydroxyphenylpyruvate dioxygenase is a relatively novel target site for triketone herbicides. The inhibitory activity of 34 natural products of various structural classes on HPPD and the mode of interaction of selected natural products were investigated.

Last Modified: 9/23/2014