Submitted to: Journal of Molecular Evolution
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: April 17, 2002
Publication Date: N/A
Interpretive Summary: In most insects and other egg-laying animals, developing eggs gather and store a protein in the yolk called "vitellogenin" (Vg). However, some flies use an unrelated kind of protein called "yolk protein" (YP) instead of Vg. Moths have both Vg and a less abundant protein called YP2 or "egg-specific protein" (ESP). Both the fly and the moth proteins are related to a class of proteins called lipases, which are found in many organisms, and which help break down fats. In this paper, an analysis of the amino acid (protein building blocks) sequences shows that the YP's of flies and the YP2/ESP's of moths are evolutionarily related to each other.