|Shivaprasad, H - UNIVERSITY OF CALIFORNIA|
|Crespo, Rocio - UNIVERSITY OF CALIFORNIA|
|Hall, Cheryl - ZACKY FARMS, INC.|
Submitted to: American Veterinary Medical Association Abstract
Publication Type: Abstract Only
Publication Acceptance Date: July 14, 2001
Publication Date: N/A
Technical Abstract: The pathology of a natural outbreak of reticuloendotheliosis virus (REV) infection in breeder and market age turkeys is described. Fifty breeder and market age turkeys between the ages of 13 and 54 weeks were involved in this REV outbreak. Thirty birds had involvement of the liver characterized by either pale diffuse moderate to severe enlargement or with multiple pale white nodules. Most of the thirty birds had pale enlarged spleens and a few birds had pale enlarged kidneys, thymus, cecal tonsils, mucosa of the intestine, conjunctiva, etc. Microscopically, there was infiltration of neoplastic lymphocytes in the organs described above. In addition, bone marrow, adrenal, ovary, thyroid and rarely bursa of Fabricius were also infiltrated with neoplastic lymphocytes. Blood chemistry analysis from 14 birds revealed increased levels of aspartate aminotransferase, creatine kinase, lactate dehydrogenase and alkaline phosphatase in most birds; one bird had severe leukopenia.