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United States Department of Agriculture

Agricultural Research Service

Title: Genetically Engineered Vaccines for Control of Avian Influenza

Author
item Swayne, David

Submitted to: Latin American Poultry Congress
Publication Type: Proceedings
Publication Acceptance Date: October 4, 2001
Publication Date: October 9, 2001

Interpretive Summary: Interpretive Summary not required.

Technical Abstract: Avian influenza is a disease of poultry caused by an orthomyxovirus and impacts international trade. Control programs for AI varies, but has included use of vaccines. However, vaccination should only be viewed as a single tool in an overall comprehensive control strategy that utilizes biosecurity, surveillance and education. Various vaccines are effective against AI and include conventional inactivated AI vaccines to newer genetically engineered vaccines such as vectored viruses, subunit proteins and DNA vaccines. The genetically engineered vaccines protect from clinical signs and death, and reduce replication of field virus with a homologous hemagglutinin subtype. These vaccines also have some advantages over inactivated virus vaccines by preventing interference with surveillance programs. This information will be helpful in international control of avian influenza.

Last Modified: 11/27/2014
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