|Middelhoven, Wouter - WAGENINGEN UNIV., NL|
Submitted to: Antonie Van Leeuwenhoek
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: November 2, 2001
Publication Date: January 20, 2003
Citation: MIDDELHOVEN, W.J., KURTZMAN, C.P. RELATION BETWEEN PHYLOGENY AND PHYSIOLOGY IN SOME ASCOMYCETOUS YEASTS. 2003. V. 83. P. 69-74. Interpretive Summary: Genetic relationships among yeasts, as well as other living organisms, can be estimated from substitutions (differences) in the gene sequences of their genetic material (DNA). This study tests the idea that closely related yeasts will have more similar growth characteristics than species that are only distantly related. The work showed that widely seen characteristics such as sugar fermentation are common to both closely and distantly related species, but that ability to grow on certain unique chemicals (e.g., methanol, imidazole, isobutanol) is shared by only small groups of closely related species. If a yeast is needed to modify an unusual agriculturally important chemical in an industrial fermentation process, it is likely that closely related species can also grow on this compound and could be tested as potentially better choices for a particular requirement. In contrast, distantly related species are unlikely to have the unique metabolic properties needed.