|Fettinger, James - DEP CHEM BIOCHEM, UNIV MD|
Submitted to: Phytopathology
Publication Type: Abstract Only
Publication Acceptance Date: August 12, 2000
Publication Date: N/A
Technical Abstract: Two fungi isolated from soybean cyst nematode produced inhibitors of root-knot nematode (Meloidogyne incognita) egg hatch and juvenile mobility. Bioassay-directed identification of the nematode-antagonistic compounds was undertaken. The trichothecene compounds 4,15-diacetylnivalenol and diacetoxyscirpenol were responsible in part for the inhibitory activity found in the culture broth of one of the fungi, a strain of Fusarium equiseti. Trichothecenes are mycotoxins generally having nonspecific toxicity. The nematode-antagonistic compounds from the second fungus species are currently being isolated from the culture broth by extracting with Amberlite XAD resin and purifying with Toyopearl HW40 and silica gel column chromatography and with reversed-phase HPLC. Identifying natural products from fungi associated with plant-parasitic nematodes can provide insights for new control methods.