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United States Department of Agriculture

Agricultural Research Service

Title: Fusarium Equiseti Secretes Compounds Antagonistic to Root-Knot Nematode, Meloidogyne Incognita

item Nitao, James
item Meyer, Susan
item Schmidt, Walter
item Fettinger, James - DEP CHEM BIOCHEM, UNIV MD
item Chitwood, David

Submitted to: Society of Nematology Meeting
Publication Type: Abstract Only
Publication Acceptance Date: June 24, 2000
Publication Date: N/A

Technical Abstract: Fungi isolated from soybean cyst nematode were examined for production of nematode-antagonistic compounds. Fusarium equiseti produced inhibitors of root-knot nematode (Meloidogyne incognita) egg hatch and juvenile mobility. Bioassay-guided fractionation of a culture broth extract identified two active compounds, the trichothecenes 4,15-diacetylnivalenol and diacetoxyscirpenol. Trichothecenes possess broad spectrum toxicity, limiting their usefulness as templates for control agents. A second fungus species is also being examined. An Amberlite XAD extract of the culture broth was fractionated using medium-pressure chromatography (Toyopearl resin and silica gel) and reversed-phase HPLC. The identities of the nematode-antagonistic compounds from the second fungus species are being determined. Efforts to identify natural products from fungi associated with plant-parasitic nematodes can provide lead compounds for new control agents and increase our understanding of nematode-fungus interactions.

Last Modified: 4/22/2015
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