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United States Department of Agriculture

Agricultural Research Service

Title: Analytical Sfe: Utilization in Developing Extraction and Chromatographic Processing Involving Critical Fluids

Authors
item King, Jerry
item Eller, Fred
item Taylor, Scott
item Snyder, Janet - USDA, ARS RETIRED

Submitted to: Eastern Analytical Symposium
Publication Type: Abstract Only
Publication Acceptance Date: November 16, 1999
Publication Date: N/A

Technical Abstract: Aside from its application to analytical problems, SFE instrumentation can play a critical role in the development and optimization of processing conditions for engineering applications. With the advent of automated sequential analyzers and multi-sample parallel extractor, this utilization of analytical SFE becomes an efficient tool saving considerable time and money. Analytical scale instrumentation can be modified to screen catalysts for reaction chemistry, perform fractionation, and optimize extraction conditions for natural product isolation. These modes of application will be illustrated utilizing enzyme catalysis in the presence of SC-CO2, enrichment of phospholipids for nutraceutical use, and enhanced extraction of the oil from cedarwood. Conceptualization of how available multi-sample SFE instrumentation might be used in a combinatorial mode will be illustrated. This will include multi-tubular, isothermal based equipment, mixed modules operating at multiple temperaturs and pressures, multi-variable sequential instrumentation, and scaled-up versions of these concepts. The advantages of conducting reaction and extraction chemistries in critical fluid media with respect to solvent reduction and environmentally benign processing, and in a combinatorial fashion, suggest many possibilities for technological applications.

Last Modified: 9/10/2014
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