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ARS Home » Midwest Area » Peoria, Illinois » National Center for Agricultural Utilization Research » Mycotoxin Prevention and Applied Microbiology Research » Research » Publications at this Location » Publication #326609
Title: Building the tree of life from scratch: an end-to-end work flow for phylogenomic studies

Author
item ZHOU, XIAOFAN - Vanderbilt University
item SHEN, XING-XING - Vanderbilt University
item PERIS, DAVID - University Of Wisconsin
item Kurtzman, Cletus
item HITTINGER, CHRIS - University Of Wisconsin
item ROKAS, ANTONIS - Vanderbilt University

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 3/1/2016
Publication Date: 3/1/2016
Citation: Zhou, X., Shen, X., Peris, D., Kurtzman, C.P., Hittinger, C.T., Rokas, A. 2016. Building the tree of life from scratch: an end-to-end work flow for phylogenomic studies [abstract].

Interpretive Summary:

Technical Abstract: Whole genome sequences are rich sources of information about organisms that are superbly useful for addressing a wide variety of evolutionary questions. Recent progress in genomics has enabled the de novo decoding of the genome of virtually any organism, greatly expanding its potential for understanding the biology and evolution of the full spectrum of biodiversity. However, the increasing diversity of sequencing technologies, assays, and de novo assembly algorithms has also augmented the complexity of de novo genome sequencing projects in non-model organisms. For example, as part of our Dimensions of Biodiversity grant we are sequencing the genomes of all known 1,000 yeast species in the yeast subphylum to gain insights into their metabolism, ecology, and biodiversity. The anticipated flood of genome data demands efficient workflows for genomic, evolutionary, and phylogenomic analyses. Here, we present and end-to-end workflow for such studies that encompasses both the design and execution of de novo genome sequencing and downstream phylogenomic analyses.