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Title: Avian influenza virus with Hemagglutinin-Neuraminidase combination H8N8, isolated in Russia

Author
item SIVAY, MARIYA - Novosibirsk State University
item SHARSHOV, KIRILL - Novosibirsk State University
item Pantin Jackwood, Mary
item MUZYKA, VLADIMIR - Novosibirsk State University
item SHESTOPALOV, ALEXANDER - Novosibirsk State University

Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 5/16/2014
Publication Date: 6/5/2014
Publication URL: http://handle.nal.usda.gov/10113/59838
Citation: Sivay, M.V., Sharshov, K.A., Pantin-Jackwood, M.J., Muzyka, V.V., Shestopalov, A.M. 2014. Avian influenza virus with Hemagglutinin-Neuraminidase combination H8N8, isolated in Russia. Genome Announcements. 2(3):e00545-14. DOI: 10.1128/genomeA.00545-14.

Interpretive Summary: A rarely identified influenza A virus of H8N8 subtype was isolated from a common teal in Western Siberia. The virus was completely sequenced and the genome analysis showed that all genes belong to avian influenza virus (AIV) Eurasian lineages. The virus didn’t produce clinical signs when given to chickens. This information is important for understanding the evolutionary ecology of AIV.

Technical Abstract: This study reports the genome sequence of an avian influenza virus (AIV) subtype H8N8 isolated in Russia. The genome analysis shows that all genes belong to AIV Eurasian lineages. The PB2 gene was similar to a Mongolian low pathogenic (LP) AIV H7N1 and a Chinese high pathogenic (HP) AIV H5N2.